Chemistry is traditionally divided into organic and inorganic chemistry. The former is the study of compounds containing at least one carbon-hydrogen bonds. 83237-15-4, Name is 3-(3,5-Di-tert-butyl-1-hydroxy-4-oxocyclohexa-2,5-dien-1-yl)propanoic acid, molecular formula is C17H26O4, belongs to thiazolidines compound, is a common compound. In a patnet, author is Bhat, Mahima, once mentioned the new application about 83237-15-4, COA of Formula: C17H26O4.
Synthesis and evaluation of thiazolidinone-pyrazole conjugates as anticancer and antimicrobial agents
Aim: To synthesize a series of new thiazolidinone-pyrazole hybrids (5a-o) and assess their anticancer (in vitro and in vivo) and antimicrobial activities. Results: The compounds 5h (against Ehrlich ascites carcinoma cells), 5e and 5i (against the human breast cancer [MDA-MB231] cell line) exhibited potent anticancer activity. All the compounds except 5g and 5e found to be less toxic for the human dermal fibroblast cells. The effective interactions of the compounds in silico with MDM2 exemplified their inhibitory potency. The derivatives also showed moderate antimicrobial activity. Conclusion: The halogen atoms on various positions of the N-arylamino ring played an advantageous role in elevating the potency of the molecules. Thus, these conjugates could be used as a lead for further optimization to achieve promising therapeutics. [GRAPHICS] .
We¡¯ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, 83237-15-4. The above is the message from the blog manager. COA of Formula: C17H26O4.
Reference:
Thiazolidine – Wikipedia,
,Thiazolidine – ScienceDirect.com