Catalysts are substances that increase the reaction rate of a chemical reaction without being consumed in the process. 542-05-2, Name is 3-Oxopentanedioic acid, SMILES is O=C(CC(O)=O)CC(O)=O, belongs to thiazolidines compound. In a document, author is Patil, Shital Manoj, introduce the new discover, Safety of 3-Oxopentanedioic acid.
Comparative Study of Various Non-Nucleoside Reverse Transcriptase Inhibitors on Different Reverse Transcriptase Enzyme
Context: Acquired immunodeficiency Syndrome (AIDS) is caused by Human immunodeficiency virus type 1 (HIV-1). 4-Thiazolidone nulecus is the target pharmacophore which have diverse biological activities including anti HIV activity. Aim: To study binding behavior of thiazolidinone derivatives on four different crystal structures of HIV-1RT. Material and Method: Binding pattern of some thiazolidinone derivatives was gauged by molecular docking studies on four different receptors bearing PDB code 1ZD1, 1RT2, 1KLM, 1FKP of HIV-RT enzyme using V. Life MDS software. Result and Discussion: The studies revealed hydrogen bonds, hydrophobic interaction and pi-pi interactions playing significant role in binding of the molecules to the enzyme. Conclusion: Interactions, binding energy and dock score of molecule 6 was comparable with the standard drugs.
The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 542-05-2 is helpful to your research. Safety of 3-Oxopentanedioic acid.
Reference:
Thiazolidine – Wikipedia,
,Thiazolidine – ScienceDirect.com