With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.1438-16-0,3-Aminorhodanine,as a common compound, the synthetic route is as follows.
A solution of 3,5-dibromo-2-hydroxybenzaldehyde (104 mg, 0.371 mmol) in methanol (1 ML) was added to a solution of 3-aminorhodanine (50 mg, 0.337 mmol) in methanol (5 ML) and the mixture allowed to stand at room temperature.. After 1 h, the precipitate was filtered, washed (methanol, ether) and dried to give the title compound (93 mg, 67%) as a pale yellow solid. LCMS m/e 409, 411, 413 [M+H]+.
1438-16-0 3-Aminorhodanine 74033, athiazolidine compound, is more and more widely used in various.
Reference£º
Patent; SmithKline Beecham Corporation; US6720345; (2004); B1;,
Thiazolidine – Wikipedia
Thiazolidine – ScienceDirect.com