A new synthetic route of 2199-44-2

After consulting a lot of data, we found that this compound(2199-44-2)Name: Ethyl 3,5-Dimethyl-2-pyrrolecarboxylate can be used in many types of reactions. And in most cases, this compound has more advantages.

Name: Ethyl 3,5-Dimethyl-2-pyrrolecarboxylate. So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic. Compound: Ethyl 3,5-Dimethyl-2-pyrrolecarboxylate, is researched, Molecular C9H13NO2, CAS is 2199-44-2, about 5-Unsubstituted 2-pyrrolecarboxaldehydes for porphyrin synthesis and the cyanovinyl protecting group.

(Cyanovinyl)pyrroles I (R = Me, R1 = Et, octyl; R = Et, R1 = Me) derived from the Knoevenagel condensation of benzyl 5-formyl-2-pyrrolecarboxylates with NCCH2CO2Me were employed in a facile sequence of 4 steps to produce, regioselectively, 2-pyrrolecarboxaldehydes II, important intermediates for porphyrin synthesis. Each step proceeded in 90-95% yield, making II available smoothly from benzyl 5-methyl-2-pyrrolecarboxylates in 7 steps, with an overall yield of 66-72%.

After consulting a lot of data, we found that this compound(2199-44-2)Name: Ethyl 3,5-Dimethyl-2-pyrrolecarboxylate can be used in many types of reactions. And in most cases, this compound has more advantages.

Reference:
Thiazolidine – Wikipedia,
Thiazolidine – ScienceDirect.com