A new application about Dimethylmalonate

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In an article, author is Chavan, Anusaya S., once mentioned the application of 108-59-8, Safety of Dimethylmalonate, Name is Dimethylmalonate, molecular formula is C5H8O4, molecular weight is 132.1146, MDL number is MFCD00008460, category is thiazolidines. Now introduce a scientific discovery about this category.

Baker’s yeast catalyzed one-pot synthesis of bioactive 2-[benzylidene(or pyrazol-4-ylmethylene) hydrazono]-1,3-thiazolidin-4-one-5-yl-acetic acids

An efficient and simple one-pot protocol has been developed for synthesis of substituted derivatives of 2-hydrazono-4-thiazolidinone-5-acetic acids 4a-j and 6a-g by cyclocondensation of aryl/pyrazolyl aldehyde, thiosemicarbazide and maleic anhydride in acetonitrile in the presence of readily available whole cell biocatalyst, baker’s yeast (Saccharomyces cerevisiae). The reaction is enhanced by ultrasonication.

If you are interested in 108-59-8, you can contact me at any time and look forward to more communication. Safety of Dimethylmalonate.

Reference:
Thiazolidine – Wikipedia,
,Thiazolidine – ScienceDirect.com