Electric Literature of 76186-04-4, Chemistry is the experimental science by definition. We want to make observations to prove hypothesis. For this purpose, we perform experiments in the lab. 76186-04-4, Name is (S)-4-Isopropylthiazolidine-2-thione,introducing its new discovery.
Stereoselective synthesis of maresin 1
Maresin 1 is a potent anti-inflammatory and pro-resolving lipid mediator derived from docosahexaenoic acid. The total synthesis of maresin 1 is achieved in 10 steps and in 7% overall yield. The Evans-Nagao aldol reaction between (2E,4E)-5-bromopenta-2,4-dienal and different chiral auxiliaries is investigated. The reported synthesis is efficient and highly stereoselective, affording multi-milligram quantities of this biologically interesting lipid mediator.
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Reference£º
Quinuclidine – Wikipedia,
Quinuclidine | C7H758N | ChemSpider