1055361-35-7, An article , which mentions 1055361-35-7, molecular formula is C19H11F3N2O4S. The compound – 4-(4-((2,4-Dioxothiazolidin-5-ylidene)methyl)-2-methoxyphenoxy)-3-(trifluoromethyl)benzonitrile played an important role in people’s production and life.
Synthesis of quinolin-2-one alkaloid derivatives and their inhibitory activities against HIV-1 reverse transcriptase
Based on an established common pharmacophore of HIV-1 non-nucleoside reverse transcriptase inhibitors (NNTTIs), a series of quinolin-2-one derivatives were synthesized and assayed for their in vitro activities against HIV-1 reverse transcriptase (RT) for the first time. Some of the tested compounds were active against HIV-1 RT. Compounds 4a2 and 4d2 showed inhibitory activities with IC50 values of 0.21 and 0.15 muM, respectively, with a mode of interaction with RT residues of the allosteric pocket similar to that of efavirenz.
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Quinuclidine – Wikipedia,
Quinuclidine | C7H883N | ChemSpider