Quality Control of Ethyl 3,5-Dimethyl-2-pyrrolecarboxylate. So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic. Compound: Ethyl 3,5-Dimethyl-2-pyrrolecarboxylate, is researched, Molecular C9H13NO2, CAS is 2199-44-2, about Synthesis of a chiral 3,3′-di-tert-butyl-2,2′-bipyrrole.
Di-Et 3,3′-di-tert-butyl-4,4′-dimethyl-2,2′-bipyrrole-5,5′-dicarboxylate (I) was synthesized in four steps from Et 3,5-dimethyl-1H-pyrrole-2-carboxylate. The CH2 hydrogens of the Et ester groups of the former are diastereotopic in the 1H-NMR, consistent with axial chirality of the bipyrrole and restricted rotation about the 2,2′-bipyrrole bond, due to the tert-Bu groups. X-ray anal. of crystalline I shows that the pyrrole rings are twisted out of coplanarity by 84.5°.
Although many compounds look similar to this compound(2199-44-2)Quality Control of Ethyl 3,5-Dimethyl-2-pyrrolecarboxylate, numerous studies have shown that this compound(SMILES:O=C(C1=C(C)C=C(C)N1)OCC), has unique advantages. If you want to know more about similar compounds, you can read my other articles.
Reference:
Thiazolidine – Wikipedia,
Thiazolidine – ScienceDirect.com