Application In Synthesis of Ethyl 3,5-Dimethyl-2-pyrrolecarboxylate. So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic. Compound: Ethyl 3,5-Dimethyl-2-pyrrolecarboxylate, is researched, Molecular C9H13NO2, CAS is 2199-44-2, about Some mercuration reactions of substituted pyrroles.
Mercuration of N-unsubstituted pyrroles with mercury(II) acetate results in immediate precipitation of the N-mercurated derivative, which is insoluble in virtually all organic solvents. If the pyrrole N atom is protected (e.g. with Me, CH2OCH2Ph, or CO2CMe3) then mercuration takes place efficiently at unsubstituted pyrrole carbons. Subsequent palladium/olefin (Heck-type) reactions afford the corresponding pyrrole acrylate when, for example, the olefin is Me acrylate; deprotection (when the N-substituent is CH2OCH2Ph or CO2CMe3) then affords the required carbon-substituted pyrrole. Attempts to deprotect the N-methylpyrroles were unsuccessful.
Although many compounds look similar to this compound(2199-44-2)Application In Synthesis of Ethyl 3,5-Dimethyl-2-pyrrolecarboxylate, numerous studies have shown that this compound(SMILES:O=C(C1=C(C)C=C(C)N1)OCC), has unique advantages. If you want to know more about similar compounds, you can read my other articles.
Reference:
Thiazolidine – Wikipedia,
Thiazolidine – ScienceDirect.com