In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called Acid dissociation constants of some benzo-substituted 2-chlorobenzimidazoles, published in 1966, which mentions a compound: 15965-55-6, mainly applied to BENZIMIDAZOLES DISSOCN; DISSOCN BENZIMIDAZOLES; CHLOROBENZIMIDAZOLES DISSOCN, Safety of 2-Chloro-7-nitro-1H-benzo[d]imidazole.
The measurements of the apparent pK were measured in water with 2% MeOH at a constant ionic strength of 0.5 from derivatives by substitution in the 5(6) and 4(7) positions. The following values were obtained: H, 9.3; 5(6) Me, 9.5; 5(6) Cl, 8.5; 5(6) NO2, 7.4; 4(7) Me, 9.6; 4(7) Cl 8.4; 4(7) NO2 7.5. The acidity justifies the hypothesis that in the presence of methoxy ions the compounds are transformed in the conjugate bases and without nucleophilic reactivity. With piperidine and PhSH the nucleophilic reaction is possible.
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Reference:
Thiazolidine – Wikipedia,
Thiazolidine – ScienceDirect.com