Skowronek, Pawel; Lightner, David A. published the article 《Synthesis of a chiral 3,3′-di-tert-butyl-2,2′-bipyrrole》. Keywords: chiral bipyrroledicarboxylate derivative preparation x ray; crystal structure chiral bipyrroledicarboxylate derivative; mol structure chiral bipyrroledicarboxylate derivative; atropisomer bipyrroledicarboxylate derivative preparation x ray.They researched the compound: Ethyl 3,5-Dimethyl-2-pyrrolecarboxylate( cas:2199-44-2 ).Recommanded Product: Ethyl 3,5-Dimethyl-2-pyrrolecarboxylate. Aromatic heterocyclic compounds can be divided into two categories: single heterocyclic and fused heterocyclic. In addition, there is a lot of other information about this compound (cas:2199-44-2) here.
Di-Et 3,3′-di-tert-butyl-4,4′-dimethyl-2,2′-bipyrrole-5,5′-dicarboxylate (I) was synthesized in four steps from Et 3,5-dimethyl-1H-pyrrole-2-carboxylate. The CH2 hydrogens of the Et ester groups of the former are diastereotopic in the 1H-NMR, consistent with axial chirality of the bipyrrole and restricted rotation about the 2,2′-bipyrrole bond, due to the tert-Bu groups. X-ray anal. of crystalline I shows that the pyrrole rings are twisted out of coplanarity by 84.5°.
As far as I know, this compound(2199-44-2)Recommanded Product: Ethyl 3,5-Dimethyl-2-pyrrolecarboxylate can be applied in many ways, which is helpful for the development of experiments. Therefore many people are doing relevant researches.
Reference:
Thiazolidine – Wikipedia,
Thiazolidine – ScienceDirect.com