Machine Learning in Chemistry about 2199-44-2

This literature about this compound(2199-44-2)Category: thiazolidinehas given us a lot of inspiration, and I hope that the research on this compound(Ethyl 3,5-Dimethyl-2-pyrrolecarboxylate) can be further advanced. Maybe we can get more compounds in a similar way.

Category: thiazolidine. The reaction of aromatic heterocyclic molecules with protons is called protonation. Aromatic heterocycles are more basic than benzene due to the participation of heteroatoms. Compound: Ethyl 3,5-Dimethyl-2-pyrrolecarboxylate, is researched, Molecular C9H13NO2, CAS is 2199-44-2, about Pyrroles with isoprenoid substituents. Author is Nizhnik, A. N.; Mironov, A. F..

Pyrroles I (R1 = CO2Et, R2 = Me, CHO; R1 = I, R2 = CHO, 4,4,6-trimethyl-m-dioxan-2-yl; R1 = H, R2 = CHO) were prepared in 53-92% yield, e.g., acylation of 2,4-dimethyl-5-carbiethoxypyrrole with Me[MeCHCH2CH2CH2]3COCl gave 53% I (R1 = CO2Et, R2 = Me) (II). Treatment of II with NaBH4 gave 96% III [R1 = CH(OH)(CH2CH2CH2CHMe)3Me], which was dehydrated to give 93% III [R1 = CH:CH(CH2CH2CHMeCH2)3H]. III [R1 = CH2CH2(CH2CH2CHMeCH2)3H, CCl:CH(CH2CH2CHMeCH2)3H, CC(CH2CH2CHMeCH2)3H] were also prepared

This literature about this compound(2199-44-2)Category: thiazolidinehas given us a lot of inspiration, and I hope that the research on this compound(Ethyl 3,5-Dimethyl-2-pyrrolecarboxylate) can be further advanced. Maybe we can get more compounds in a similar way.

Reference:
Thiazolidine – Wikipedia,
Thiazolidine – ScienceDirect.com