So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Rhode, Constantin; Lemke, Jessica; Lieb, Max; Metzler-Nolte, Nils researched the compound: Bromoferrocene( cas:1273-73-0 ).Safety of Bromoferrocene.They published the article 《Synthesis of perfluoroalkylthio-substituted ferrocenes》 about this compound( cas:1273-73-0 ) in Synthesis. Keywords: ferrocene perfluoroalkylthio preparation redox reaction potential electrochem; trifluoromethylation ferrocene nucleophilic substitution reaction. We’ll tell you more about this compound (cas:1273-73-0).
Mono- and bis(trifluoromethylthio)-substituted and perfluorooctanesulfonylferrocene derivatives were prepared by nucleophilic substitution reactions on the ferrocene core. Thus, Hg(SCF3)2 was activated in situ by Cu and used for nucleophilic displacement reactions of bromide. Trifluoromethylsulfonylferrocene was not accessible by this method. The reaction of lithioferrocene with trifluoromethylsulfonyl chloride gave chloroferrocene in small yield, presumably due to the high lattice energy of solid LiF. On the other hand, the known trifluoromethylferrocene was obtained as the only isolable compound from the photochem. reaction of CF3SSCF3 with ferrocene. The same product was detected in small amounts in the reaction of chloromercuryferrocene with trifluoromethylsulfonyl chloride. It thus appears that most established methods for trifluoromethylation of purely organic compounds fail for ferrocene due to concurring redox reactions. The new compounds have been comprehensively characterized by elemental analyses, NMR and IR spectroscopy, mass spectrometry, and electrochem. The SCF3 group appears to be almost as electron-withdrawing as a trifluoromethyl group on the ferrocene core.
In addition to the literature in the link below, there is a lot of literature about this compound(Bromoferrocene)Safety of Bromoferrocene, illustrating the importance and wide applicability of this compound(1273-73-0).
Reference:
Thiazolidine – Wikipedia,
Thiazolidine – ScienceDirect.com