So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Engvild, K. C. researched the compound: 2-(7-Bromo-1H-indol-3-yl)acetic acid( cas:63352-97-6 ).SDS of cas: 63352-97-6.They published the article 《Preparation of chlorinated 3-indolylacetic acids》 about this compound( cas:63352-97-6 ) in Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry. Keywords: indoleacetic acid chloro; phenylhydrazine cyclization formylpropionate; hydrazine phenyl reaction formylpropionate; propionate formyl reaction phenylhydrazine. We’ll tell you more about this compound (cas:63352-97-6).
Indoleacetic acids I (Rn = 4-Cl, 6-Cl) were prepared in 38-40% yield by reaction of the resp. chloro(diethylaminomethyl)indole with NaCN followed by hydrolysis. I (Rn = 5-Cl, 7-Cl, 4,6-Cl2, 4,7-Cl2, 5,7-Cl2, 6,7-Cl2, 5-Cl-7-Me, 7-Br) were prepared in 7-28% yield by reaction of HCOCH2CH2CO2H with the appropriate phenylhydrazine hydrochlorides.
There are many compounds similar to this compound(63352-97-6)SDS of cas: 63352-97-6. if you want to know more, you can check out my other articles. I hope it will help you，maybe you’ll find some useful information.
Reference:
Thiazolidine – Wikipedia,
Thiazolidine – ScienceDirect.com