In 2021.0 ORG LETT published article about ASYMMETRIC-SYNTHESIS; 3+2 CYCLOADDITION; CYCLOPROPANES; RINGS in [McDaniel, Jade; Farley, Christopher A.; Shi, Qing; Hynes, John, Jr.; Dhar, T. G. Murali; Marcoux, David] Bristol Myers Squibb, Dept Discovery Chem, Princeton, NJ 08540 USA; [Ramirez, Antonio; Han, Arthur; Gallagher, William P.; Gonzalez-Bobes, Francisco; Coombs, John R.] Bristol Myers Squibb, Chem Proc Dev, New Brunswick, NJ 08903 USA; [Sandhu, Bhupinder; Sarjeant, Amy] Bristol Myers Squibb, Mat Sci & Engn, New Brunswick, NJ 08903 USA in 2021.0, Cited 59.0. The Name is Chalcone. Through research, I have a further understanding and discovery of 94-41-7. Safety of Chalcone
The use of the unprecedented annulating reagents methyl N-(tert-butylsulfinyl)-4-chlorobutanimidate and methyl N-(tert-butylsulfinyl)-5-bromopentanimidate enables the diastereoselective preparation of 5- and 6-membered carbocycles bearing three contiguous stereocenters. These synthons undergo cycloaddition with a variety of Michael acceptors to form cyclopentane/cyclohexane rings with excellent stereochemical control, generating only one of the eight possible diastereomers. This novel methodology has enabled the highly enantioselective and high yielding synthesis of novel chemotypes of pharmacological relevance.
Safety of Chalcone. About Chalcone, If you have any questions, you can contact McDaniel, J; Farley, CA; Ramirez, A; Sandhu, B; Sarjeant, A; Shi, Q; Han, A; Gallagher, WP; Hynes, J; Dhar, TGM; Gonzalez-Bobes, F; Coombs, JR; Marcoux, D or concate me.
Reference:
Thiazolidine – Wikipedia,
,Thiazolidine – ScienceDirect.com