An article Catalytic Asymmetric Three-component Hydroacyloxylation/ 1,4-Conjugate Addition of Ynamides WOS:000539628500001 published article about ORTHO-QUINONE METHIDES; CYCLIZATION; CHEMISTRY; LIGANDS in [Li, Xiangqiang; Jiang, Mingyi; Zhan, Tangyu; Cao, Weidi; Feng, Xiaoming] Sichuan Univ, Coll Chem, Key Lab Green Chem & Technol, Minist Educ, Chengdu 610064, Peoples R China in 2020, Cited 58. Category: thiazolidines. The Name is Chalcone. Through research, I have a further understanding and discovery of 94-41-7
A highly enantioselective three-component hydroacyloxylation/1,4-conjugate addition ofortho-hydroxybenzyl alcohols, ynamides and carboxylic acids was developed under mild reaction conditions in the presence of a chiralN,N ‘-dioxide/Sc(OTf)(3)complex, which went throughin situgeneratedortho-quinone methides with alpha-acyloxyenamides, delivering a range of corresponding chiral alpha-acyloxyenamides derivatives containinggem(1,1)-diaryl skeletons in moderate to good yields with excellenteevalues. The scale-up experiment and further derivation showed the practicality of this catalytic system. In addition, a possible catalytic cycle and transition state model was proposed to elucidate the origin of the stereoselectivity based on X-ray crystal structure of the alpha-acyloxyenamide intermediate and product.
Category: thiazolidines. About Chalcone, If you have any questions, you can contact Li, XQ; Jiang, MY; Zhan, TY; Cao, WD; Feng, XM or concate me.
Reference:
Thiazolidine – Wikipedia,
,Thiazolidine – ScienceDirect.com