SDS of cas: 94-41-7. Recently I am researching about CATALYZED ASYMMETRIC ALKYLATION; MORITA-BAYLIS-HILLMAN; KINETIC RESOLUTION; SECONDARY PHOSPHINE; PHOSPHORUS LIGANDS; STEREOGENIC PHOSPHINES; ALLYLIC ALKYLATION; METAL-FREE; DESYMMETRIZATION; HYDROGENATION, Saw an article supported by the NSFCNational Natural Science Foundation of China (NSFC) [21672068, 21725203]; 973 programNational Basic Research Program of China [2015CB856600]; Ministry of Education (PCSIRT)Program for Changjiang Scholars & Innovative Research Team in University (PCSIRT); Fundamental Research Funds for the Central UniversitiesFundamental Research Funds for the Central Universities. Published in ROYAL SOC CHEMISTRY in CAMBRIDGE ,Authors: Zhu, RY; Chen, L; Hu, XS; Zhou, F; Zhou, J. The CAS is 94-41-7. Through research, I have a further understanding and discovery of Chalcone
We report the highly enantioselective synthesis of P-chiral tertiary phosphine oxides featuring an ethynyl group via Cu(i)-catalyzed azide-alkyne cycloaddition. Newly developed chiral pyridinebisoxazolines (PYBOX) bearing a bulky C4 shielding group play an important role in achieving excellent enantioselectivity while suppressing side bis-triazoles formation in desymmetrizing prochiral diethynylphosphine oxides. Notably, by tuning the size of the C4 shielding group, it is possible to achieve excellent remote enantiofacial control in desymmetrizing phosphole oxide-diynes with the prochiral P-center farther from the ethynyl group by four covalent bonds. Time-dependent enantioselectivity is observed for these desymmetric CuAAC reactions, suggesting a synergic combination of a desymmetrization and a kinetic resolution, and our ligands prove to be better than unmodified PYBOX in both steps. This finding contributes to a highly enantioselective kinetic resolution of racemic ethynylphosphine oxides. The resulting chiral ethynylphosphine oxides are versatile P-chiral synthons, which can undergo a number of diversifying reactions to enrich structural diversity.
About Chalcone, If you have any questions, you can contact Zhu, RY; Chen, L; Hu, XS; Zhou, F; Zhou, J or concate me.. SDS of cas: 94-41-7
Reference:
Thiazolidine – Wikipedia,
,Thiazolidine – ScienceDirect.com