COA of Formula: C6H11NS2, Chemistry is a science major with cience and engineering. The main research directions are chemical synthesis,preparation and modification of special coatings. In some cases, the catalyzed mechanism may include additional steps.In a article, 76186-04-4, molcular formula is C6H11NS2, introducing its new discovery.
The first diastereoselective synthesis of aryloxyphosphoramidate prodrugs of 3?-deoxy-2?,3?-didehydrothymidinemonophosphate (d4TMP) was recently reported. The synthetic approach utilized the chiral auxiliary (S)-4-isopropylthiazolidine-2-thione (2). For this strategy, a stereochemically pure phosphorodiamidate intermediate was needed. The diastereoselective formation of this key compound was investigated by using different phenols and L-alanine methyl or benzyl ester. Generally, the reaction with 3- or 4-substituted phenols led to significantly better diastereoselectivities compared to their 2-substituted counterparts. Moreover, variation of the ester group in the amino acid residue resulted in no significant differences with regard to the obtained diastereoselectivity. From the reported results, a model for the transition state was elaborated. Finally, eight new (S P)-arylphosphoramidates were synthesized with very high diastereoselectivities (up to ? 95 % de) and tested for their anti-HIV potency, showing a tendency for higher antiviral activity from the (S P) diastereomers.
A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 76186-04-4
Reference：
Quinuclidine – Wikipedia,
Quinuclidine | C7H711N | ChemSpider