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Twenty-four asymptomatic, HIV-1-seropositive subjects with CD4 cell counts of ?400/mul participated in a Phase I/II, dose escalation trial of intravenous L-2-oxothiazolidine-4-carboxylic acid (OTC: Procysteine). Four groups of six subjects each were consecutively assigned to receive OTC at an initial dose of 3, 10, 30, or 100 mg/kg, followed by the same dose given twice weekly for 6 weeks. Increases in whole-blood glutathione were observed in the highest dosage group after 6 weeks of therapy. No effects on changes in CD4 cell counts, viral load, or proviral DNA frequency were observed among the four dosage groups, although a decline in beta2-microglobulin levels was apparent in the highest dosage group. One subject withdrew due to headaches; other probable adverse events including rash, flushing, pruritus, lightheadedness, and diminished concentration were self-limited.
Because enzymes can increase reaction rates by enormous factors and tend to be very specific, Reference of 19771-63-2, typically producing only a single product in quantitative yield, they are the focus of active research.you can also check out more blogs about Reference of 19771-63-2
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Quinuclidine – Wikipedia,
Quinuclidine | C7H673N | ChemSpider