New Advances in Chemical Research, May 2021. Application of 185137-29-5, Enzyme inhibitors cause a decrease in the reaction rate of an enzyme-catalyzed reaction by binding to a specific portion of an enzyme and thus slowing or preventing a reaction from occurring. In a document type is Article, and a compound is mentioned, 185137-29-5, (S)-4-Phenylthiazolidine-2-thione, introducing its new discovery.
In contrast to alcohols and amines, racemic lactams and thiolactams cannot be resolved directly via enzymatic acylation or classical resolution. Asymmetric N-acylation promoted by amidine-based catalysts, particularly Cl-PIQ 2 and BTM 3, provides a convenient method for the kinetic resolution of these valuable compounds and often achieves excellent levels of enantioselectivity in this process. Density functional theory calculations indicate that the reaction occurs via N-acylation of the lactim tautomer and that cation-pi interactions play a key role in the chiral recognition of lactam substrates.
Because enzymes can increase reaction rates by enormous factors and tend to be very specific, Application of 185137-29-5, typically producing only a single product in quantitative yield, they are the focus of active research.you can also check out more blogs about Application of 185137-29-5
Reference：
Quinuclidine – Wikipedia,
Quinuclidine | C7H784N | ChemSpider