With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.26364-65-8,2-Cyanoimino-1,3-thiazolidine,as a common compound, the synthetic route is as follows.,26364-65-8
Under nitrogen protection, add 25g (0.197mol) HRB-1365-2 to the three-necked bottle.(2-cyanoimino-1,3-thiazolidine molecular formula: C4H5N3S) compound, adding 300 mL of methanol,With stirring, 23 g of triethylamine was added, and 26 g (0.230 mol) was added.Compound HRB-1365-1 (Cysteamine molecular formula:C2H7NS), stir the reaction at room temperature for four hours,After LC-MS was monitored, the methanol was distilled off under reduced pressure and the solid was filtered.The solid distilled water was washed with 50 ml, and dried to obtain a white solid HRB-1365 (amino thiol thiazoline molecular formula: C6H9N3S2) 16 g,
As the paragraph descriping shows that 26364-65-8 is playing an increasingly important role.
Reference£º
Patent; Yang Wenmao; (12 pag.)CN103387550; (2016); B;,
Thiazolidine – Wikipedia
Thiazolidine – ScienceDirect.com