Properties and Exciting Facts About 2,2-Bis(hydroxymethyl)butyric acid

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In an article, author is Devi, N. Saritha, once mentioned the application of 10097-02-6, Computed Properties of C6H12O4, Name is 2,2-Bis(hydroxymethyl)butyric acid, molecular formula is C6H12O4, molecular weight is 148.16, MDL number is MFCD00190088, category is thiazolidines. Now introduce a scientific discovery about this category.

SYNTHESIS AND SCREENING N-(2, 4 ‘-DIOXO-1, 2-DIHYDRO-3 ‘ H-SPIRO [INDOLE-3, 2 ‘-[1,3]THIAZOLIDIN]-3 ‘-YL)-2-HYDROXYBENZAMIDES FOR ANTI-BACTERIAL ACTIVITY

A novel synthesis of N-(2, 4′-dioxo-1, 2-dihydro-3’H-spiro [indole-3, 2′-[1, 3] thiazolidin]-3’-yl)-2-hydroxybenzamide derivatives were synthesized by cyclization of isatin hydrazones with thioglycolic acid. The synthesized compounds were characterized by spectral data (IR, H-1-NMR, Mass) and evaluated for antibacterial activity against various strains of bacteria at the concentrations of 200 mu g/ml. Among the tested compounds X(i) is highly active against E. coli, X(f) is active against B. subtilis, X(h) is active against S. aureus and X(c) is active against S. typhi.

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Reference:
Thiazolidine – Wikipedia,
,Thiazolidine – ScienceDirect.com