The important role of Rhodanine

Application of 141-84-4, One of the oldest and most widely used commercial enzyme inhibitors is aspirin, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. you can also check out more blogs about 141-84-4.

Application of 141-84-4, The transformation of simple hydrocarbons into more complex and valuable products via catalytic C¨CH bond functionalisation has revolutionised modern synthetic chemistry. 141-84-4, Name is Rhodanine, SMILES is O=C1CSC(=S)N1, belongs to thiazolidines compound. In a article, author is Sayed, Samia M., introduce new discover of the category.

Synthesis and Reactivity of Phenylthiourea Derivatives: An Efficient Synthesis of New Thiazole-Based Heterocycles

Reaction of 1-(5-acetyl-4-methylthiazol-2-yl)-3-phenylthiourea 2 with hydrazonoyl chlorides (3a, 3b, 3c, 3d, 3e, 3f) and 9 yielded the corresponding (thiazolyl)imino-1,3,4-thiadiazole derivatives (6a, 6b, 6c, 6d, 6e, 6f) and 12, respectively. Reaction of 2 with ethyl chloroacetate 13 gave (thiazolyl)imino-1,3-thiazolidin-4-one derivative 15, which upon condensation with aromatic aldehyde derivatives yielded the 5-benzylidene derivatives (16a, 16b). In addition, treatment of 2 with 3-chloropenta-2,4-dione 17 afforded the corresponding (thiazolyl)imino-1,3-thiazole derivative 19. The newly synthesized compounds were confirmed from their elemental analyses and spectral data.

Application of 141-84-4, One of the oldest and most widely used commercial enzyme inhibitors is aspirin, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. you can also check out more blogs about 141-84-4.

Reference:
Thiazolidine – Wikipedia,
,Thiazolidine – ScienceDirect.com