As a common heterocyclic compound, it belong thiazolidine compound,Thiazolidin-2-one,2682-49-7,Molecular formula: C3H5NOS,mainly used in chemical industry, its synthesis route is as follows.,2682-49-7
Example 5 Preparation of 3-(2-nitrophenylmethyl)-2-thiazolidinone A mixture containing 3.09 g (0.03 mol) of 2-thiazolidinone, 11.2 g of potassium carbonate, 1.8 g of potassium hydrogen carbonate, 0.5 ml of water, 30 ml of methyl isobutyl ketone and 6.5 g (0.03 mol) of 2-nitrobenzyl bromide is refluxed for 6 hours, then cooled down and thoroughly mixed with 50 ml of water. The mixture is filterred and the clear filtrate is separated. The organic phase is washed with 10 ml of water, dried and evaporated. The oily residue is recrystallized from ethanol to give 2.65 g (37.0%) of the title compound, m.p.: 92-93 C. IR (KBr): 1670 cmmin1 (C=O) 1525, 1345 cmmin1 (NO2) 1H-NMR (CDCl3): 3.1-3.8 ppm (m, 4H, 2CH2) 4.9 ppm (s, 2H,CH2) 7.2-8.3 ppm (m, 4H, ArH).
With the synthetic route has been constantly updated, we look forward to future research findings about Thiazolidin-2-one,belong thiazolidine compound
Reference£º
Patent; RICHTER GEDEON VEGYESZETI GYAR R.T.; EP320910; (1989); A1;,
Thiazolidine – Wikipedia
Thiazolidine – ScienceDirect.com