Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics, 6117-80-2, Name is (Z)-But-2-ene-1,4-diol, SMILES is OC/C=CCO, belongs to thiazolidines compound. In a document, author is Patel, Navin B., introduce the new discover, Formula: C4H8O2.
Synthesis and evaluation of antibacterial and antifungal activities of 4-thiazolidinones and 2-azetidinones derivatives from chalcone
(E)-3-(thiophen-2-yl)-1-(4-methylphenyl)-prop-2-en-1-one 1 was obtained from the reaction of thiophene-2-aldehyde with p-methyl acetophenone. The treatment of 1 with guanidine nitrate produced 4-thiophen-2-yl-6-(4-methylphenyl)-pyrimidin-2-ylamine 2. The synthesis of N-substituted benzylidine-4-(4-methylphenyl)-6-(thiophen-2-yl) pyrimidin-2-amines 3a-j was performed by the treatment of compound 2 with the corresponding aromatic aldehydes. The reaction of 3a-j with thioglycolic acid and thiolactic acid formed the corresponding 3-[4-(4-methyl-phenyl)-6-thiophen-2-yl-pyrimidin-2-yl]-2-(substituted-phenyl)-thiazolidin-4-ones 4a-j and 3-[4-(4-methyl-phenyl)-6-thiophen-2-yl-pyrimidin-2-yl]-2-(substituted-phenyl)-5-methyl-thiazolidin-4-ones 5a-j and with chloroacetylchloride, it gives 3-chloro-1-[4-(4-methyl-phenyl)-6-thiophen-2-yl-pyrimidin-2-yl]-4-(substituted-phenyl)-azetidin-2-ones 6a-j. Newer analogues were characterized by infrared spectrum, H-1 nuclear magnetic resonance, C-13 nuclear magnetic resonance spectroscopy and elemental analyses. The newly synthesized analogues were then examined for their antimicrobial activity against some bacterial and fungal strains as two Gram-negative bacteria (Escherichia coli, Pseudomonas aeruginosa), two Gram-positive bacteria (Staphylococcus aureus, Streptococcus pyogenes) and two fungal species (Candida albicans, Aspergillus niger, Aspergillus Clavatus) to develop a novel class of antimicrobial agents.
The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 6117-80-2 is helpful to your research. Formula: C4H8O2.
Reference:
Thiazolidine – Wikipedia,
,Thiazolidine – ScienceDirect.com