Related Products of 2421-28-5, Chemo-enzymatic cascade processes are invaluable due to their ability to rapidly construct high-value products from available feedstock chemicals in a one-pot relay manner. 2421-28-5, Name is Benzophenone-3,3′,4,4′-tetracarboxylic dianhydride, SMILES is O=C(C1=CC2=C(C(OC2=O)=O)C=C1)C3=CC4=C(C(OC4=O)=O)C=C3, belongs to thiazolidines compound. In a article, author is Cui, Liying, introduce new discover of the category.
Organocatalytic Enantioselective alpha-Amination of Thiazol-4-one-5-carboxylates with Azodicarboxylates
An effective method for the asymmetric synthesis of 5-hydrazinothiazol-4-one-5-carboxylates was developed. The tetrasubstituted chiral carbon center was generated by asymmetric amination of thiazol-4-one-5-carboxylate with azodicarboxylate catalyzed by a bifunctional squaramide-based (1R,2R)-cyclohexane-1,2-diamine backbone in good to excellent yields (40-96%) with high levels of enantioselectivity (92-98% ee). A representative transformation of the amination product to a biologically important 1,3,4-oxadiazol-2(3H)-one is achieved without any appreciable loss in enantioselectivity. Additionally, upon treatment with NaBH3CN, the amination product could also be converted into a biologically important thiazolidin-4-one derivative in good yield without any loss of stereochemical integrity.
Related Products of 2421-28-5, Consequently, the presence of a catalyst will permit a system to reach equilibrium more quickly, but it has no effect on the position of the equilibrium as reflected in the value of its equilibrium constant.I hope my blog about 2421-28-5 is helpful to your research.
Reference:
Thiazolidine – Wikipedia,
,Thiazolidine – ScienceDirect.com