Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. 593-85-1, Name is guanidinecarbonate, molecular formula is C3H12N6O3, belongs to thiazolidines compound. In a document, author is Singh, Ravi P., introduce the new discover, Name: guanidinecarbonate.
Novel thiazolidines: Synthesis, antiproliferative properties and 2D-QSAR studies
A series of N-substituted (Z)-2-imino-(5Z)-ylidene thiazolidines/thiazolidin-4-ones were synthesized and their antiproliferative activities against colon (HCT-116) and breast (MCF7) cancer cell lines were evaluated utilizing an MTT growth assay. A 2D-QSAR investigation was conducted to probe and validate the obtained antiproliferative properties for the thiazolidine derivatives. The majority of the thiazolidines exhibit higher potency against a colon cancer cell line relative to the standard reference. The p-halophenylimino p-anisylidene derivatives exhibited the highest anti-proliferative activity against HCT116 relative to control (IC50 = 8.9-10.0 mu M compared to 20.4 mu M observed for 5-fluorouracil as positive control). An X-ray study confirmed the Z, Z’-configurations for two examples of the synthesized compounds.
Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law. In my other articles, you can also check out more blogs about 593-85-1. Name: guanidinecarbonate.
Reference:
Thiazolidine – Wikipedia,
,Thiazolidine – ScienceDirect.com