Electric Literature of 76186-04-4, In homogeneous catalysis, the catalyst is in the same phase as the reactant. The number of collisions between reactants and catalyst is at a maximum.In a patent, Electric Literature of 76186-04-4, name is (S)-4-Isopropylthiazolidine-2-thione, introducing its new discovery.
Highly Enantioselective Claisen-Type Acylation and Dieckmann Annulation
Enantioselective Claisen condensation reactions between various esters 1a-f and 3-acyl-4(S)-IPTT 2a,b employing lithium isopropylcyclohexylamide and HMPA gave acylated products 3a-j in 29-77percent yield and in 22-97percent ee.Asymmetric Dieckmann-type annulation of 4a with KH in DMF followed by methanolysis afforded bicyclic beta-keto methyl ester 6a in 69percent overall yield and in 96percent ee.
Because enzymes can increase reaction rates by enormous factors and tend to be very specific, Electric Literature of 76186-04-4, typically producing only a single product in quantitative yield, they are the focus of active research.you can also check out more blogs about Electric Literature of 76186-04-4
Reference£º
Quinuclidine – Wikipedia,
Quinuclidine | C7H746N | ChemSpider