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Synthesis of C2-symmetric bisthiazolidine ligands derived from L-cysteine
Treatment of L-cysteine esters and thiazolidine-4-carboxylic esters with an excess of paraformaldehyde in the presence of trifluoroacetic acid provides C2-symmetric N,N?-methylene-bisthiazolidines in good yield.
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Reference£º
Quinuclidine – Wikipedia,
Quinuclidine | C7H787N | ChemSpider