Some scientific research tips on 1273-73-0

Compound(1273-73-0)SDS of cas: 1273-73-0 received a lot of attention, and I have introduced some compounds in other articles, similar to this compound(Bromoferrocene), if you are interested, you can check out my other related articles.

SDS of cas: 1273-73-0. So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic. Compound: Bromoferrocene, is researched, Molecular C10BrFe, CAS is 1273-73-0, about The electrochemical cleavage of carbon-halogen bonds of haloferrocenes.

Cyclic voltammetric studies for chloroferrocene  [1273-74-1], bromoferrocene  [1273-73-0], and iodoferrocene  [1273-76-3] in ethylene glycol di-Me ether at -45° were reported. The cyclic voltammogram and the absorption spectrum of the solution after the exhaustive controlled-potential reduction for the reduction step of haloferrocene show a quant. formation of ferrocene and a cleavage of the C-halogen bond of haloferrocene.

Compound(1273-73-0)SDS of cas: 1273-73-0 received a lot of attention, and I have introduced some compounds in other articles, similar to this compound(Bromoferrocene), if you are interested, you can check out my other related articles.

Reference:
Thiazolidine – Wikipedia,
Thiazolidine – ScienceDirect.com

What I Wish Everyone Knew About 15965-55-6

Compound(15965-55-6)Product Details of 15965-55-6 received a lot of attention, and I have introduced some compounds in other articles, similar to this compound(2-Chloro-7-nitro-1H-benzo[d]imidazole), if you are interested, you can check out my other related articles.

Epoxy compounds usually have stronger nucleophilic ability, because the alkyl group on the oxygen atom makes the bond angle smaller, which makes the lone pair of electrons react more dissimilarly with the electron-deficient system. Compound: 2-Chloro-7-nitro-1H-benzo[d]imidazole, is researched, Molecular C7H4ClN3O2, CAS is 15965-55-6, about Synthesis and antitrichomonal activity of azinium (azolium) 4-nitrobenzimidazolate betaines and their derivatives.Product Details of 15965-55-6.

Among the many attractive types of heterocyclic betaines, the inner salts of azinium azolates and azolium azolates are few and scattered. The antiprotozoal activity (in vitro) against Trichomonas vaginalis of a variety of mesomeric betaines of pyridinium azolates, their N-azolylpyridinium salts, and N-5-nitrobenzimidazol-2-ylpyridinium derivatives, e.g. 1-(5-nitro-1H-benzimidazol-2-yl)-2,4,6-triphenylpyridinium salts was reported. In the present study, 1-(4-nitro-1H-benzimidazol-2-yl)pyridinium salts were prepared and tested against T. vaginalis in vitro and in vivo.

Compound(15965-55-6)Product Details of 15965-55-6 received a lot of attention, and I have introduced some compounds in other articles, similar to this compound(2-Chloro-7-nitro-1H-benzo[d]imidazole), if you are interested, you can check out my other related articles.

Reference:
Thiazolidine – Wikipedia,
Thiazolidine – ScienceDirect.com

Never Underestimate the Influence Of 114527-53-6

Compound(114527-53-6)Name: 1,2,3,4-Tetrahydroquinoline-3-carboxylic acid received a lot of attention, and I have introduced some compounds in other articles, similar to this compound(1,2,3,4-Tetrahydroquinoline-3-carboxylic acid), if you are interested, you can check out my other related articles.

In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called Traceless Electrophilic Amination for the Synthesis of Unprotected Cyclic β-Amino Acids, published in 2019-07-03, which mentions a compound: 114527-53-6, mainly applied to cyclic beta amino acid preparation electrophilic amination, Name: 1,2,3,4-Tetrahydroquinoline-3-carboxylic acid.

Electrophilic aminations involve an umpolung of a nitrogen atom, providing an alternate, distinctive synthetic strategy. The recent advent of various designed O-substituted hydroxylamines has significantly advanced this research field. An underappreciated issue is atom economy of the transformations: The necessary activating group on the oxygen atom is left in coproduced waste. Herein, the authors describe Rh-catalyzed electrophilic amination of substituted isoxazolidin-5-ones for the synthesis of unprotected, cyclic β-amino acids featuring either benzo-fused or spirocyclic scaffolds. Using the cyclic hydroxylamines allows for retaining both nitrogen and oxygen functionalities in the product. The traceless, redox neutral process proceeds on a gram scale with as little as 0.1 mol % catalyst loading. In contrast to related electrophilic aminations in the literature, a series of mechanistic experiments suggests a unique pathway involving spirocyclization, followed by the skeletal rearrangement. The insights provided herein shed light on a nuanced reactivity of the active species, Rh-nitrenoid generated from the activated hydroxylamine, and extend the knowledge on electrophilic aromatic substitutions.

Compound(114527-53-6)Name: 1,2,3,4-Tetrahydroquinoline-3-carboxylic acid received a lot of attention, and I have introduced some compounds in other articles, similar to this compound(1,2,3,4-Tetrahydroquinoline-3-carboxylic acid), if you are interested, you can check out my other related articles.

Reference:
Thiazolidine – Wikipedia,
Thiazolidine – ScienceDirect.com

New explortion of 2199-44-2

Compound(2199-44-2)Reference of Ethyl 3,5-Dimethyl-2-pyrrolecarboxylate received a lot of attention, and I have introduced some compounds in other articles, similar to this compound(Ethyl 3,5-Dimethyl-2-pyrrolecarboxylate), if you are interested, you can check out my other related articles.

Reference of Ethyl 3,5-Dimethyl-2-pyrrolecarboxylate. So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic. Compound: Ethyl 3,5-Dimethyl-2-pyrrolecarboxylate, is researched, Molecular C9H13NO2, CAS is 2199-44-2, about Double-helical dinuclear bis(dipyrromethene) complexes Formed by self-assembly.

Bis(dipyrromethene) ligands linked by an alkyl spacer between β and β’ positions (I; n = 1, 2, 3) give helical dimers or monomers, dependent upon the length of the alkyl linker, upon complexation. Ligands consisting of methylene, ethylene, and propylene linkers -(CH2)n- (n = 1, 2, and 3) give helical dimers, while longer linking chains (n = 4, 5, or 6) give monomers or mixtures of dimers and monomers. X-ray crystal structures of the dimeric Zn complexes (n = 1, 2, and 3) reveal that the angles between dipyrromethene planes and the extent of helicity in the complexes differ as the length of the linker varies. The extent of helicity was assessed and is dependent upon the length and, specifically, the conformational preferences of the alkyl spacer unit. The presence of an ethylene linker gave complexes of greatest helicity. The use of a methylene spacer gave less helical structures upon complexation, while propylene spacers gave only slightly helical complexes. These studies identify the crucial importance that the conformational preferences of the β-β’ alkyl spacer group plays in the coordination algorithm of self-assembly to form dipyrromethene based complexes.

Compound(2199-44-2)Reference of Ethyl 3,5-Dimethyl-2-pyrrolecarboxylate received a lot of attention, and I have introduced some compounds in other articles, similar to this compound(Ethyl 3,5-Dimethyl-2-pyrrolecarboxylate), if you are interested, you can check out my other related articles.

Reference:
Thiazolidine – Wikipedia,
Thiazolidine – ScienceDirect.com

Chemical Research in 2199-44-2

Compound(2199-44-2)SDS of cas: 2199-44-2 received a lot of attention, and I have introduced some compounds in other articles, similar to this compound(Ethyl 3,5-Dimethyl-2-pyrrolecarboxylate), if you are interested, you can check out my other related articles.

The reaction of an aromatic heterocycle with a proton is called a protonation. One of articles about this theory is 《Some reactions of 2,4-dimethylmagnesylpyrrole》. Authors are Ingraffia, F..The article about the compound:Ethyl 3,5-Dimethyl-2-pyrrolecarboxylatecas:2199-44-2,SMILESS:O=C(C1=C(C)C=C(C)N1)OCC).SDS of cas: 2199-44-2. Through the article, more information about this compound (cas:2199-44-2) is conveyed.

Because of the anomalous behavior of magnesylpyrrole with SOCl2 (I) and CS2 (cf. Oddo and Mingoia, C. A. 21, 1458), it was decided to study their action as well as that of ClCO2Et (II) on a little studied derivative of pyrrole, viz., 2,4-dimethylpyrrole (III) in the form of its magnesyl derivative (IV), and on magnesylpyrroles with neg. radicals (to stabilize the ring). IV and II in anhydrous Et2O, heated, and decomposed with ice, yield Et 2,4-dimethyl-5-pyrrolecarboxylate, HN.CMe:CH.CMe:CCO2Et (V), slightly yellow, m. 124°. I in Et2O added to ice-cold IV (2 mols.) in Et2O, after standing decomposed with ice, neutralized with NaHCO3 and purified with difficulty (Et2O, petr. ether, Me2CO and C6H6), yields 3,5,3′,5′-tetramethylpyrro-(2,2′)-sulfone, (HN.CMe:CH.CMe:C)2SO2, dark violet, decomposes around 95° stable toward hot alk. hydroxides, is not reduced by Zn and AcOH, is decomposed with evolution of H2S by Sn in hot HCl. Ag derivative, probably an α’-derivative IV and CS2 in Et2O heated, decomposed with ice, acidified with H2O4, the Et2O-soluble product treated with aqueous NaOH, and acidified when ice-cold, precipitates 2,4-dimethyl-5-dithiopyrrolecarboxylic acid, HN.CMe:CH.CMe:CC(:S)SH (VI), also obtained directly but very impure by drying the Et2O-soluble portion (loc. cit.). It is unstable and immediately oxidizes to 2,4-dimethylthiopyrrole disulfide, [HN.CMe:CH.CMe:CC(:S)S-]2, red, m. 156°. With neutral Pb(OAc)2, the aqueous Na salt (VII) of VI precipitates the Pb salt, [HN.CMe:CH.CMe:CC(:S)S]2Pb, yellow. In darkness, aqueous VI and AgNO3 precipitate the Ag salt, HN.CMe:CH.CMe:CC(:S)SAg, brick-red. No Zn salt is precipitated from aqueous VII and Zn(OAc)2. It was then to be determined whether with a compound containing a neg. CO2Et group, e. g., V, the reaction with EtMgBr is normal, and if so to determine the behavior of the new metal derivative in comparison with III. Actually V and EtMgBr in anhydrous Et2O evolve C2H6 and form the magnesyl derivative (VIII), BrMgN.CMe:CH.CMe:CCO2Et or HN.CMe:C(MgBr).CMe:CCO2Et, yellowish oil. Heated with CS2 or with AcCl in anhydrous Et2O, VIII remains unaltered. This incapacity to react probably depends upon the assumption of the enolic form, N:CMe.CH:CMe.C:C(OMgBr)OEt, as was found with alkyl pyrryl ketones by Oddo (C. A. 19, 2492; Gazz. chim. ital. 40, ii, 15(1910); cf. C. A. 4, 2460).

Compound(2199-44-2)SDS of cas: 2199-44-2 received a lot of attention, and I have introduced some compounds in other articles, similar to this compound(Ethyl 3,5-Dimethyl-2-pyrrolecarboxylate), if you are interested, you can check out my other related articles.

Reference:
Thiazolidine – Wikipedia,
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Simple exploration of 1273-73-0

Compound(1273-73-0)Application In Synthesis of Bromoferrocene received a lot of attention, and I have introduced some compounds in other articles, similar to this compound(Bromoferrocene), if you are interested, you can check out my other related articles.

The reaction of an aromatic heterocycle with a proton is called a protonation. One of articles about this theory is 《Ferrocene and related organometallic π-complexes. IV. Some Ullmann reactions of haloferrocenes》. Authors are Rausch, Marvin D..The article about the compound:Bromoferrocenecas:1273-73-0,SMILESS:Br[C-]12[Fe+2]3456789([C-]%10C6=C7C8=C9%10)C1=C3C4=C25).Application In Synthesis of Bromoferrocene. Through the article, more information about this compound (cas:1273-73-0) is conveyed.

cf. CA 54, 22540e. Haloferrocenes were found to undergo the Ullmann coupling reaction readily. Iodoferrocene (I) and Cu bronze form biferrocenyl (II) in quant. yield at 150°. Both I and 1-iodo-2-nitrobenzene (III) formed coupling products in 95-100% yield at temperatures as low as 60°. A series of ferrocenyl aryl ethers were prepared by the Ullmann condensation of I and K aryloxides. I was prepared in 60-70% yield by the reaction of chloromercuriferrocene and iodine in xylene at 75-80°, m. 49-9.5° (MeOH-H2O). Bromo- (IV) and chloroferrocene (V) were obtained by the reaction of ferrocenylboronic acid with CuBr and CuCl, resp. I (0.936 g.) and 1.9 g. Cu bronze heated 16 hrs. at 140-50°, the mixture extracted with hot C6H6, and the extract evaporated gave 0.510 g. II, m. 239-40° (decomposition). In experiments in which less pure I was used the yield of II was appreciably less than quant. Similar reactions in which I was replaced by IV and V gave yields of 97 and 65% II, resp. I (0.405 g.), 0.83 g. Cu bronze, and 4 g. biphenyl heated 16 hrs. at 130°, and then 3 hrs. at 158-60°, and the residues chromatographed gave a total of 76% II. Reactions in which HCONMe2 was used as solvent and diluent gave mostly ferrocene. When the reaction was carried out using Zn and heating 19 hrs. at 150° and the product chromatographed on Al2O3, 17% II was obtained. II was less soluble in common organic solvents than ferrocene. The infrared and ultraviolet spectra of II were discussed. III (4.98 g.) and 12.7 g. Cu bronze heated 60 hrs. at 60° gave 2.3 g. 2,2′-dinitrobiphenyl, m. 125°. Similarly, 4.98 g. 1,3-I(O2N)C6H4 and 12.7 g. Cu bronze afforded a crude product which when chromatographed on Al2O3 gave 1% 3,3′-dinitrobiphenyl, m. 197-8°, and 4.20 g. unchanged material. In a reaction similar to that described above 20.4 g. PhI and 1 g. Cu bronze gave 16 g. unchanged PhI and no trace of Ph2. I (0.624 g.) and 1.28 g. Cu bronze gave 97% II. I (0.405 g.), 0.324 g. III, and 1.65 g. Cu bronze gave a crude product which when chromatographed on Al2O3 gave 71% II, and 7.5% 2-nitrophenylferrocene, m. 116-17°. Ferrocenyl aryl ethers were prepared by the following typical procedure. 2-Naphthol (1.44 g.) and 0.28 g. KOH heated at 150° until all the KOH dissolved, 0.936 g. I and 0.02 g. Cu bronze added, the mixture heated 16 hrs. at 115°, cooled, the contents washed with 10% KOH, extracted with refluxing C6H6, and the product chromatographed on Al2O3 gave 0.11 g. ferrocene and 0.12 g. ferrocenyl 2-naphthyl ether, m. 143-3.5° (heptane). The following further ferrocenyl aryl ethers were prepared (aryl group, m.p., and % yield given): Ph, 93-3.5°, 28; 3-(3-phenoxyphenoxy)phenyl, 74-4.5°, 50; 2-biphenylyl, 141-2°, 62; 4-BrC6H4, 87-7.5°, 22. All ferrocenyl aryl ethers exhibited strong absorption in the 1270-1230 cm.-1 region. When heated in sealed capillaries the ethers did not appear to decompose

Compound(1273-73-0)Application In Synthesis of Bromoferrocene received a lot of attention, and I have introduced some compounds in other articles, similar to this compound(Bromoferrocene), if you are interested, you can check out my other related articles.

Reference:
Thiazolidine – Wikipedia,
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Properties and Exciting Facts About 114527-53-6

Compound(114527-53-6)Category: thiazolidine received a lot of attention, and I have introduced some compounds in other articles, similar to this compound(1,2,3,4-Tetrahydroquinoline-3-carboxylic acid), if you are interested, you can check out my other related articles.

The reaction of an aromatic heterocycle with a proton is called a protonation. One of articles about this theory is 《Synthetic sympatholytic substances in the ergotamine series. V. Some derivatives of 1,2,3,4-tetrahydroquinoline》. Authors are Chiavarelli, Stefano; Marini-Bettol, G. B..The article about the compound:1,2,3,4-Tetrahydroquinoline-3-carboxylic acidcas:114527-53-6,SMILESS:OC(=O)C1CNC2=CC=CC=C2C1).Category: thiazolidine. Through the article, more information about this compound (cas:114527-53-6) is conveyed.

cf. C.A. 46, 5602g. In connection with investigations aimed at establishing the relations between the chem. structure and biol. activity of compounds of the type of the alkaloids of Segale cornuta, it seemed of interest to study some 3-substituted derivatives of 1,2,3,4-tetrahydroquinoline (I), particularly since the structure of I is found in the lysergic acid mol. By a modification of the method of Gilman and Spatz (C.A. 35, 5495.2), 83 g. 3-quinolinecarboxylic acid (II), m. 275-6°, was obtained by refluxing 108 g. 3-cyanoquinoline (III) and 20% aqueous NaOH 2 hrs. The Na salt of II (25 g.) in 200 cc. water and 5 g. Raney Ni, hydrogenated 2 hrs. at 150° and 120 atm., filtered, the filtrate concentrated, acidified with HCl (d. 1.17) (to Congo red), and the precipitate purified by dilute EtOH yield 14 g. 1,2,3,4-tetrahydro-3-quinolinecarboxylic acid-HCl (IV), m. 236°, which with NH4OH yields the free acid, m. 145-6° (from EtOH). IV (0.2 g.) in 3 cc. anhydrous C5H5N and 1.6 g. Ac2O, refluxed 10 min., poured when cool into 10 cc. water + 6 cc. HCl, allowed to stand, and the precipitate purified by EtOH, yield the 1-Ac derivative, C12H14O2N, straw-colored, m. 152°. A suspension of 100 g. III in 1400 cc. MeOH refluxed 10 hrs. in a current of HCl gas (III.HCl forms first), most of the MeOH distilled, the residue poured into 3 l. ice-water, made alk. with K2CO3, kept ice-cold several hrs., and the precipitate purified by MeOH, yields 82 g. of Me 3-quinolinecarboxylate (V), m. 73-4°. V (36 g.) in 300 cc. MeOH with 5 g. Pd-C, hydrogenated at 60-65° under 90 atm., filtered, concentrated in vacuo, and allowed to stand, yields Me dihydro-3-quinolinecarboxylate (VI), m. 134-5°, is strongly fluorescent in Wood light (both solid and in solution), reduces neutral AgNO3 solution, is oxidized by dilute KMnO4; picrate, m. 187-9°. V (2 g.) in 50 cc. MeOH with 2 g. Raney Ni, hydrogenated 3 hrs. at 110° under 100 atm., filtered, and distilled at 115° (0.1 mm.); or 5 g. VI in 100 cc. MeOH with 4 g. Raney Ni and 1 g. 10% Pd-C, hydrogenated at 100° under 100 atm., and the product filtered, concentrated, and distilled in vacuo, yields the 1,2,3,4-tetrahydro derivative (VII), of VI, viscous oil, b0.3 124°. With HCl, it forms an HCl salt, m. 181-4°, and with picric acid a picrate, m. 151-3°. VII (1 g.) and 5-8 cc. concentrated HCl, heated in a sealed tube 3 hrs. at 100°, and the product purified by dilute EtOH, yield 1,2,3,4-tetrahydro-3-quinolinecarboxylic acid-HCl (VIII), m. 234°. N,N-Diethyl-3-quinolinecarboxamide (IX) (10 g.) in 100 cc. MeOH with 3 g. 10% Pd-C, hydrogenated 3 hrs. at 60° under 90 atm., filtered, concentrated, and the precipitate purified by EtOH, yields 1,2,3,4-tetrahydro derivative (X), m. 132-3°, forming with HCl a HCl salt, m. 160-1°. Hydrolyzed like VII, X yields VIII, m. 235-6°. 3-Aminoquinoline (XI) (144 g.) in 400 cc. tetrahydronaphthalene with 15 g. Raney Ni, hydrogenated at 55° under 90 atm., filtered, distilled in vacuo, and the residue rectified in vacuo, yields 127 g. crude product, b8 160-6°, which, fractionated and the fractions b. above 164° distilled in vacuo (0.8 mm.) at 250°, yields the 1,2,3,4-tetrahydro derivative (XII), m. 57°; picrate (from anhydrous EtOH), m. 205-6°; HCl salt (from EtOH by addition of Et2O), sinters 240°, m. 250°, turns violet by oxidation in air. XII oxidizes easily on exposure to air and light, and shows triboluminescence when rubbed with a wooden spatula. Benzoylated by the Schotten-Bauman method, XII gives a di-Bz derivative, C23H20O2N2, m. 201° (from EtOH). The distillation residue of XII (a fraction, b0.8 250°), fractionated further, gives a fraction, b0.4 234°, 3,3′-iminobis(1,2,3,4-tetrahydroquinoline) (XIII), very viscous resinous oil. With HCl, it forms a HCl salt (XIV), m. 254°, and with picric acid a picrate, m. 190-2°. In aqueous HCl solution, XIV gives with aqueous NaNO2 a yellow precipitate, which, purified by EtOH, yields the nitroso derivative, C18H18O3N6, m. 156°. Et2SO4 (9 cc.), added during 1 hr. to 15 g. XII in 200 cc. anhydrous Me2CO and 16 g. K2CO3, the mixture refluxed 6 hrs., filtered, evaporated, excess 20% aqueous NaOH added, the solution extracted with Et2O, the extract dried by K2CO3, evaporated, and the residue distilled in vacuo, yields 3-ethylamino-1,2,3,4-tetrahydroquinoline, b0.1 110-13°; picrate (from anhydrous EtOH), m. 198°. Et2SO4 (28 cc.), added during 1 hr. to 15 g. XII in 300 cc. anhydrous Me2CO and 48 g. K2CO3, the mixture refluxed 8 hrs., and the foregoing procedure followed, yields 3-diethylamino-1-ethyl-1,2,3,4-tetrahydroquinoline, b0.4 116°; picrate, m. 103-4°; HCl salt, very hygroscopic. The ultraviolet absorption spectra of II, IV, V, VI, VII, IX, X, XI, and XII are reproduced.

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Reference:
Thiazolidine – Wikipedia,
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Awesome Chemistry Experiments For 1428537-19-2

Compound(1428537-19-2)Application In Synthesis of (R)-4-(tert-Butyl)-2-(5-(trifluoromethyl)pyridin-2-yl)-4,5-dihydrooxazole received a lot of attention, and I have introduced some compounds in other articles, similar to this compound((R)-4-(tert-Butyl)-2-(5-(trifluoromethyl)pyridin-2-yl)-4,5-dihydrooxazole), if you are interested, you can check out my other related articles.

Epoxy compounds usually have stronger nucleophilic ability, because the alkyl group on the oxygen atom makes the bond angle smaller, which makes the lone pair of electrons react more dissimilarly with the electron-deficient system. Compound: (R)-4-(tert-Butyl)-2-(5-(trifluoromethyl)pyridin-2-yl)-4,5-dihydrooxazole, is researched, Molecular C13H15F3N2O, CAS is 1428537-19-2, about Ni-Catalyzed Ligand-Controlled Regiodivergent Reductive Dicarbofunctionalization of Alkenes.Application In Synthesis of (R)-4-(tert-Butyl)-2-(5-(trifluoromethyl)pyridin-2-yl)-4,5-dihydrooxazole.

Transition-metal-catalyzed dicarbofunctionalization of alkenes involving intramol. Heck cyclization followed by intermol. cross-coupling has emerged as a powerful engine for building heterocycles with sterically congested quaternary carbon centers. However, only exo-cyclization/cross-coupling products can be obtained; endo-selective cyclization/cross-coupling has not been reported yet and still poses a formidable challenge. We herein report the first example of catalyst-controlled dicarbofunctionalization of alkenes for the regiodivergent synthesis of five- and six-membered benzo-fused lactams bearing all-carbon quaternary centers. Using a chiral Pyrox- or Phox-type bidentate ligand, 5-exo cyclization/cross-couplings proceed favorably to produce indole-2-ones in good yields with excellent regioselectivity and enantioselectivities (up to 98% ee). When C6-carboxylic acid-modified 2,2′-bipyridine was used as the ligand, 3,4-dihydroquinolin-2-ones were obtained in good yields through 6-endo-selective cyclization/cross-coupling processes. This transformation is modular and tolerant of a variety of functional groups. The ligand rather than the substrate structures precisely dictates the regioselectivity pattern. Moreover, the synthetic value of this regiodivergent protocol was demonstrated by the preparation of biol. relevant mols. and structural scaffolds.

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Reference:
Thiazolidine – Wikipedia,
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Why Are Children Getting Addicted To 1273-73-0

From this literature《Electron-Transfer Properties of an Efficient Nonheme Iron Oxidation Catalyst with a Tetradentate Bispidine Ligand》,we know some information about this compound(1273-73-0)Formula: C10BrFe, but this is not all information, there are many literatures related to this compound(1273-73-0).

Formula: C10BrFe. The mechanism of aromatic electrophilic substitution of aromatic heterocycles is consistent with that of benzene. Compound: Bromoferrocene, is researched, Molecular C10BrFe, CAS is 1273-73-0, about Electron-Transfer Properties of an Efficient Nonheme Iron Oxidation Catalyst with a Tetradentate Bispidine Ligand. Author is Comba, Peter; Fukuzumi, Shunichi; Kotani, Hiroaki; Wunderlich, Steffen.

The electron-transfer properties are reported for an FeV=O complex (I) with the tetradentate bispidine ligand. The electron transfer from dibromoferrocene (Br2Fc) to I is confirmed by the UV/Vis spectral changes, with an increase of the absorption observed at 690 nm for the Br2Fc+ cation and the concomitant decrease of the absorption of I at 760 nm.

From this literature《Electron-Transfer Properties of an Efficient Nonheme Iron Oxidation Catalyst with a Tetradentate Bispidine Ligand》,we know some information about this compound(1273-73-0)Formula: C10BrFe, but this is not all information, there are many literatures related to this compound(1273-73-0).

Reference:
Thiazolidine – Wikipedia,
Thiazolidine – ScienceDirect.com

Brief introduction of 2199-44-2

From this literature《A novel route to certain 2-pyrrolecarboxylic esters and nitriles》,we know some information about this compound(2199-44-2)Safety of Ethyl 3,5-Dimethyl-2-pyrrolecarboxylate, but this is not all information, there are many literatures related to this compound(2199-44-2).

The reaction of an aromatic heterocycle with a proton is called a protonation. One of articles about this theory is 《A novel route to certain 2-pyrrolecarboxylic esters and nitriles》. Authors are Kleinspehn, Geo. G..The article about the compound:Ethyl 3,5-Dimethyl-2-pyrrolecarboxylatecas:2199-44-2,SMILESS:O=C(C1=C(C)C=C(C)N1)OCC).Safety of Ethyl 3,5-Dimethyl-2-pyrrolecarboxylate. Through the article, more information about this compound (cas:2199-44-2) is conveyed.

HON:C(CO2Et)2 (I) underwent reduction and condensation with certain β-diketones and a β-oxo aldehyde to give 2-pyrrolecarboxylic esters. Similarly, HON:C(CN)CO2Et (II) and certain β-diketones afforded 2-pyrrolecarbonitriles. The method has been applied to the synthesis of 5 previously known pyrroles. This synthetic approach constitutes the most direct route to 4 of these 5 pyrroles. A sixth and previously unreported pyrrole, 3,5-dimethyl-2-pyrrolecarbonitrile (III), also has been prepared by this method. Ac2CH2 (5.00 g.) in 26 cc. glacial AcOH heated with vigorous stirring at 80° with 13 g. NaOAc and 11 g. Zn dust, the mixture then treated with 9.47 g. I in 12 cc. AcOH and 5 cc. H2O dropwise at 95-105° during 30-40 min., heated 20 min. at 100-5°, poured with stirring into 170 cc. ice water, and refrigerated, the precipitate washed with H2O, pressed dry, dissolved in 50 cc. boiling EtOH, and filtered hot, the filtrate concentrated to 30 cc., poured into 85 cc. ice water, and refrigerated, and the crystalline deposit dried in vacuo (5.03 g.), and recrystallized twice from 95% EtOH yielded 2-carbethoxy-3,5-dimethylpyrrole (IV), m. 124-4.5°. I and Ac2CHEt (50 millimole each), b23-3.5 79-83.5°, gave by the same procedure 6.36 g. 4-Et derivative of IV, m. 90-1° (from 95% EtOH). I and Ac2CH(CH2)2CO2H (50 millimoles) treated in the same manner, the reaction mixture treated with 5 cc. concentrated HCl, and the crude product (7.08 g.) recrystallized from boiling C6H6 gave 5-carbethoxy-2,4-dimethyl-3-pyrrolepropionic acid, m. 154-6°. NaOAc (7.9 g.) added with stirring to 29 cc. glacial AcOH at 85°, the mixture treated with 7.00 g. AcCHMeCHO, 9.48 g. I, and 12 cc. glacial AcOH in 5 cc. H2O, followed by 11 g. Zn dust at 95-105°, stirred 20 min., poured into 170 cc. ice water, and refrigerated, and the deposit dissolved in 10 cc. boiling EtOH and filtered, the filtrate poured into 20 cc. ice water, and the precipitate (2.49 g.) recrystallized from 95% EtOH and then twice from isoöctane gave 2-carbethoxy-3,4-dimethylpyrrole (V), m. 75-6.5°. V heated briefly in EtOH with excess 40% aqueous CH2O and a few drops concentrated HCl yielded 5,5′-methylenebis(2-carbethoxy-3,4-dimethylpyrrole), m. 202-3°. II and Ac2CH2 (50 millimoles each) treated by the usual procedure, the crude product containing the Zn dust dissolved in 25 cc. boiling 95% EtOH, and the filtrate poured into 75 cc. ice water yielded 2.48 g. IV, m. 24-5° (recrystallized from EtOH and sublimed). Glacial AcOH (26 cc.) and 5.00 g. Ac2CH2 heated to 80°, the mixture treated consecutively with 13 g. NaOAc, 7.11 g. II, and 12 cc. AcOH in 5 cc. H2O, heated to 95°, treated during 20-5 min. with 11 g. Zn dust at 95-105°, stirred 20 min., and poured into ice water, the precipitate refrigerated, filtered off, dissolved in 15 cc. boiling EtOH, and filtered, the filtrate stirred into 30 cc. ice water and refrigerated, and the crude precipitate (2.10 g.) recrystallized twice from isoöctane yielded III, m. 75-6.5°. II and Ac2CHEt gave similarly 45% crude 4-Et derivative of III, m. 135-6°.

From this literature《A novel route to certain 2-pyrrolecarboxylic esters and nitriles》,we know some information about this compound(2199-44-2)Safety of Ethyl 3,5-Dimethyl-2-pyrrolecarboxylate, but this is not all information, there are many literatures related to this compound(2199-44-2).

Reference:
Thiazolidine – Wikipedia,
Thiazolidine – ScienceDirect.com