Month: October 2021

An article Metabolome-Based Discrimination Analysis of Shallot Landraces and Bulb Onion Cultivars Associated with Differences in the Amino Acid and Flavonoid Profiles WOS:000594964400001 published article about ALLIUM; ANTIOXIDANT; L. in [Abdelrahman, Mostafa] Aswan Univ, Fac Sci, Bot Dept, Aswan 81528, Egypt; [Ariyanti, Nur Aeni] Univ Negeri Yogyakarta, Fac Math & Nat Sci, Dept Biol Educ, Yogyakarta 55281, Indonesia; [Sawada, Yuji; Okamoto, Mami; Yamada, Yutaka; Tsugawa, Hiroshi; Hirai, Masami Yokota] RIKEN Ctr Sustainable Resource Sci, Tsurumi Ku, 1-7-22 Suehiro Cho, Yokohama, Kanagawa 2300045, Japan; [Tsuji, Fumitada] Ajinomoto Co Inc, Inst Food Sci & Technol, Kawasaki Ku, 1-1 Suzukicho, Kawasaki, Kanagawa 2108681, Japan; [Hirata, Sho] Kyushu Univ, Fac Agr, Lab Agroecol, Kasuya, Fukuoka 8112307, Japan; [Hang, Tran Thi Minh] Vietnam Natl Univ Agr, Dept Agron, Hanoi 100000, Vietnam; [Shigyo, Masayoshi] Yamaguchi Univ, Coll Agr, Grad Sch Sci & Technol Innovat, Lab Vegetable Crop Sci, Yamaguchi 7538515, Japan in 2020.0, Cited 34.0. Name: Chalcone. The Name is Chalcone. Through research, I have a further understanding and discovery of 94-41-7

Shallot landraces and varieties are considered an important genetic resource for Allium breeding due to their high contents of several functional metabolites. Aiming to provide new genetic materials for the development of a novel bulb onion cultivar derived from intraspecific hybrids with useful agronomic traits from shallots, the metabolic profiles in the bulbs of 8 Indonesian shallot landraces and 7 short-day and 3 long-day bulb onion cultivars were established using LC-Q-TOF-MS/MS. Principal component analysis, partial least squares discriminant analysis, and dendrogram clustering analysis showed two major groups; group I contained all shallot landraces and group II contained all bulb onion cultivars, indicating that shallots exhibited a distinct metabolic profile in comparison with bulb onions. Variable importance in the projection and Spearman’s rank correlation indicated that free and conjugated amino acids, flavonoids (especially metabolites having flavonol aglycone), and anthocyanins, as well as organic acids, were among the top metabolite variables that were highly associated with shallot landraces. The absolute quantification of 21 amino acids using conventional HPLC analysis showed high contents in shallots rather than in bulb onions. The present study indicated that shallots reprogrammed their metabolism toward a high accumulation of amino acids and flavonoids as an adaptive mechanism in extremely hot tropical environments.

Name: Chalcone. About Chalcone, If you have any questions, you can contact Abdelrahman, M; Ariyanti, NA; Sawada, Y; Tsuji, F; Hirata, S; Hang, TTM; Okamoto, M; Yamada, Y; Tsugawa, H; Hirai, MY; Shigyo, M or concate me.

Reference:
Thiazolidine – Wikipedia,
,Thiazolidine – ScienceDirect.com

SDS of cas: 78-39-7. In 2019.0 J AM CHEM SOC published article about C-H ACTIVATION; ORGANOBORONIC ACIDS; INTERMOLECULAR AMINOACETOXYLATION; CYCLIZATION REACTION; C(SP(3))-H BONDS; TERMINAL ALKENES; DIFUNCTIONALIZATION; CONSTRUCTION; FUNCTIONALIZATION; CARBOAMINATION in [Baik, Mu-Hyun; Hong, Sungwoo] Korea Adv Inst Sci & Technol, Dept Chem, Daejeon 34141, South Korea; Inst for Basic Sci Korea, Ctr Catalyt Hydrocarbon Functionalizat, Daejeon 34141, South Korea in 2019.0, Cited 94.0. The Name is 1,1,1-Triethoxyethane. Through research, I have a further understanding and discovery of 78-39-7.

A palladium(II)-catalyzed 1,1-difunctionalization of unactivated terminal and internal alkenes via addition of two nucleophiles was developed using a cationic palladium(II) complex. The palladacycle generated in situ as a result of a regioselective addition of a nucleophile to the alkene can readily undergo regioselective beta-hydride elimination and migratory insertion with a cationic palladium catalyst. The resulting eta(3)-pi-allyl palladium(II) complex is the key intermediate that reacts with a second nucleophile to furnish the desired 1,1-difunctionalization of the alkene. Under the optimized reaction conditions, a wide range of indoles and anilines add to alkene units of 3-butenoic or 4-pentenoic acid derivatives to afford the synthetically useful gamma,gamma- or delta,delta-difunctionalized products with excellent regiocontrol. Furthermore, by employing internal hydroxyl or acid groups and external carbon nucleophiles, this transformation enables unsymmetric 1,1-difunctionalization to forge challenging and important oxo quaternary carbon centers. Combining experiments and DFT calculations on the mechanism of the reaction is investigated in detail.

SDS of cas: 78-39-7. About 1,1,1-Triethoxyethane, If you have any questions, you can contact Jeon, J; Ryu, H; Lee, C; Cho, D; Baik, MH; Hong, S or concate me.

Reference:
Thiazolidine – Wikipedia,
,Thiazolidine – ScienceDirect.com

SDS of cas: 94-41-7. Authors Sarojini, P; Jeyachandran, M; Sriram, D; Ranganathan, P; Gandhimathi, S in ELSEVIER published article about in [Sarojini, Perumal] Sri Ramasamy Naidu Mem Coll, Dept Chem, Sattur 626203, Tamil Nadu, India; [Jeyachandran, Malaichamy; Gandhimathi, S.] Sri Paramakalyani Coll, Post Grad & Res Dept Chem, Alwarkurichi, India; [Jeyachandran, Malaichamy; Gandhimathi, S.] Manonmaniam Sundaranar Univ, Tirunelveli 627412, Tamil Nadu, India; [Sriram, Dharmarajan] Birla Inst Technol & Sci Pilani, Dept Pharm, Hyderabad Campus, Hyderabad 500078, India; [Ranganathan, Palraj] Natl Taipei Univ Technol, Inst Organ & Polymer Mat, 1,Sec 3,Chung Hsiao East Rd, Taipei 10608, Taiwan in 2021.0, Cited 33.0. The Name is Chalcone. Through research, I have a further understanding and discovery of 94-41-7

Novel 2-(aryloxymethyl)aziridines and 2((3-aryl-1-phenylallyloxy)methyl)aziridine derivatives were prepared via ring-opening reaction of epoxides. The synthesized derivatives were characterized by using elemental analysis (EA), FT-IR, C-13 NMR, and H-1 NMR. The in vitro antitubercular activities of the synthesized compounds were evaluated against Mycobacterium tuberculosis H37Rv (MTB H37Rv) strain using MTT-MABA assay. All the aziridine derivatives exhibited improved persuasive antitubercular activity against MTB H37Rv in comparison with standard drugs. Among the tested compounds, 2-(naphthalene-1-yloxy) methyl aziridine (5b), 2-(naphthalene-2-yloxy)methylaziridine (5c), 2(m-tolyloxymethyl)aziridine (5e), 2-(3-(4-methoxyphenyl)-1-phenylalloxy)methylaziridine (12b) and 2-(3(2-chlorophenyl)-1-phenylallyloxy)methylaziridine (12c) revealed promising activity against MTh H37Rv. Specifically, compound 5b and 12 b showed three-times more active (MIC = 0.5 mu g/mL) than the standard drugs ethambutol (MIC = 1.56 mu g/mL) and ciprofloxacin (MIC = 1.56 mu g/mL). (C) 2021 Elsevier B.V. All rights reserved.

About Chalcone, If you have any questions, you can contact Sarojini, P; Jeyachandran, M; Sriram, D; Ranganathan, P; Gandhimathi, S or concate me.. SDS of cas: 94-41-7

Reference:
Thiazolidine – Wikipedia,
,Thiazolidine – ScienceDirect.com

Recently I am researching about HYDROGEN-PEROXIDE; CYCLOPENTADECANONE MONOOXYGENASE; MICROBIOLOGICAL TRANSFORMATIONS; LACTONES; ACID; CATALYSTS; KETONES; ROUTE; LIGANDS, Saw an article supported by the National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [21890723, 21625205]; Fundamental Research Funds for the Central UniversitiesFundamental Research Funds for the Central Universities [2012017yjsy001]. Published in ROYAL SOC CHEMISTRY in CAMBRIDGE ,Authors: Wu, WB; Cao, WD; Hu, LF; Su, ZS; Liu, XH; Feng, XM. The CAS is 94-41-7. Through research, I have a further understanding and discovery of Chalcone. Safety of Chalcone

Regioselectivity is a crucial issue in Baeyer-Villiger (BV) oxidation. To date, few reports have addressed asymmetric BV oxidation of 3-substituted cycloketones due to the high difficulty of controlling regio- and stereoselectivity. Herein, we report the asymmetric BV oxidation of 3-substituted and meso-disubstituted cycloketones with chiral N,N ‘-dioxide/Sc(iii) catalysts performed in three ways: classical kinetic resolution, parallel kinetic resolution and desymmetrization. The methodology was applied in the total and formal synthesis of bioactive compounds and natural products. Control experiments and calculations demonstrated that flexible and adjustable catalysts played a significant role in the chiral recognition of substrates.

About Chalcone, If you have any questions, you can contact Wu, WB; Cao, WD; Hu, LF; Su, ZS; Liu, XH; Feng, XM or concate me.. Safety of Chalcone

Reference:
Thiazolidine – Wikipedia,
,Thiazolidine – ScienceDirect.com

I found the field of Chemistry very interesting. Saw the article Acid-Catalyzed Pseudo Five-Component Annulation for a General One-Pot Synthesis of 2,4,6-Triaryl Pyrimidines published in 2020.0. HPLC of Formula: C15H12O, Reprint Addresses Ma, YM (corresponding author), Taizhou Univ, Sch Pharmaceut & Chem Engn, Taizhou 318000, Peoples R China.; Ma, YM (corresponding author), Zhejiang Chinese Med Univ, Sch Pharmaceut Sci, Hangzhou 310053, Peoples R China.. The CAS is 94-41-7. Through research, I have a further understanding and discovery of Chalcone

A facile and general synthesis of 2,4,6-triaryl pyrimidines has been developed. It involves a one-pot [2+1+1+1+1] pseudo five-component annulation of one methyl ketone, two aldehydes and two NH4OAc catalyzed by TfOH. One C-C and four C-N bonds are formed during the oxidative annulation process. The reaction shows good tolerance of many important functional groups in air and produces only water as the coproduct, making this methodology a highly versatile alternative to the existing methods for structuring pyrimidine framework.

HPLC of Formula: C15H12O. About Chalcone, If you have any questions, you can contact Ding, YX; Ma, RC; Hider, RC; Ma, YM or concate me.

Reference:
Thiazolidine – Wikipedia,
,Thiazolidine – ScienceDirect.com

Pang, YY; Xiao, HS; Ou, WT; Zhang, XS; Wang, XJ; Huang, SP in [Pang, Yiying; Xiao, Hesheng; Ou, Wentao; Zhang, Xuesong; Wang, Xiaoji] Jiangxi Sci & Technol Normal Univ, Sch Life Sci, Nanchang, Jiangxi, Peoples R China; [Wang, Xiaoji] Dongguan Univ Technol, Sch Chem Engn & Energy Technol, Dongguan, Guangdong, Peoples R China; [Huang, Shuangping] Taiyuan Univ Technol, Coll Biomed Engn, Taiyuan, Shanxi, Peoples R China published A concise total synthesis of (-)-gamma-lycorane via an aromatic C-H alkylation of unactivated secondary alkyl iodide in 2020.0, Cited 37.0. HPLC of Formula: C8H18O3. The Name is 1,1,1-Triethoxyethane. Through research, I have a further understanding and discovery of 78-39-7.

A concise and straightforward total synthetic approach towards lycorine-type alkaloid (-)-gamma-lycorane has been achieved in 7 steps. The key feature of the route is the employment of a palladium-catalyzed aromatic C-H alkylation of unactivated secondary alkyl iodide. The synthetic protocols also involve a palladium-catalyzed deracemization of allylic carbonate, a Johnson-Claisen rearrangement and an iodocyclization. (C) 2020 Elsevier Ltd. All rights reserved.

About 1,1,1-Triethoxyethane, If you have any questions, you can contact Pang, YY; Xiao, HS; Ou, WT; Zhang, XS; Wang, XJ; Huang, SP or concate me.. HPLC of Formula: C8H18O3

Reference:
Thiazolidine – Wikipedia,
,Thiazolidine – ScienceDirect.com

Wang, LD; Liu, TT in [Wang, Liandi; Liu, Tingting] Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Liaoning, Peoples R China; [Liu, Tingting] Henan Acad Sci, Inst Chem, Zhengzhou 450002, Henan, Peoples R China published Transfer hydrogenation of ketones catalyzed by 2,6-bis(triazinyl) pyridine ruthenium complexes: The influence of alkyl arms in 2019.0, Cited 42.0. COA of Formula: C15H12O. The Name is Chalcone. Through research, I have a further understanding and discovery of 94-41-7.

The transfer hydrogenation of ketones catalyzed by transition metal complexes has attracted much attention. A series of ruthenium(11) complexes bearing 2,6-bis(5,6-dialkyl-1,2,4-triazin-3-yl)pyridine ligands (R-BTPs) were synthesized and characterized by NMR analysis and X-ray diffraction. These ruthenium (II) complexes were applied in the transfer hydrogenation of ketones. Their different catalytic activity were attributed to the alkyl arms on the 2,6-bis(5,6-dialkyl-1,2,4-triazin-3-yl)pyridine. As the length of the alkyl arms rising, the catalytic activities of the complex catalysts decreased. By means of 0.4 mol % catalyst RuCl2(PPh3)(3-methylbutyl-BTP) in refluxing 2-propanol, a variety of ketones were reduced to their corresponding alcohols with >95% conversion over a period of 3 h. (C) 2019 Elsevier Science. All rights reserved. (C) 2019 Elsevier Ltd. All rights reserved.

About Chalcone, If you have any questions, you can contact Wang, LD; Liu, TT or concate me.. COA of Formula: C15H12O

Reference:
Thiazolidine – Wikipedia,
,Thiazolidine – ScienceDirect.com

Recently I am researching about CONJUGATED MICROPOROUS POLYMER; METAL NANOPARTICLES; GAS-SORPTION; PALLADIUM NANOPARTICLES; FRAMEWORK; STORAGE; DESIGN; NANOCATALYSTS; PD-2(DBA)(3); FABRICATION, Saw an article supported by the Science and Engineering Research Board (SERB), New Delhi [SB/S2/JCB-52/2014]; Council of Scientific and Industrial Research (CSIR), New DelhiCouncil of Scientific & Industrial Research (CSIR) – India; university grants commission (UGC)University Grants Commission, India. Published in ACADEMIC PRESS INC ELSEVIER SCIENCE in SAN DIEGO ,Authors: Yadav, C; Maka, VK; Payra, S; Moorthy, JN. The CAS is 94-41-7. Through research, I have a further understanding and discovery of Chalcone. Formula: C15H12O

In spite of the fact that a variety of reactions have been exploited for creation of innumerable porous organic polymers (POPs), aldol condensation reactions between aldehydes and ketones leading to enones remain unutilized quite inexplicably. We surmised that the enone functionality can be exploited for stabilization of Pd akin to the manner of Pd(0) in Pd-2(dba)(3) by developing POPs based on aldol condensation reactions of polycarbonyl compounds with dialdehydes, and that such materials can be employed for catalytic transformations. By subjecting rationally designed tri-/tetraacetyl-functionalized aryl amines to aldol condensations with terephthalaldehyde, three different POPs, i.e., TPAPOPs 1-3, that feature enone functionalities have been synthesized and shown to exhibit palpable gas sorption properties. Remarkably, inverse uptake for sorption of H-2 over N-2 was observed for all POPs. As surmised, the representative POP, i.e., TPAPOP-1, was found to stabilize in situ-generated Pd(0) nanoparticles to enable application of the resultant material, i.e., Pd@TPAPOP-1, as a recyclable heterogeneous catalyst for a number of organic transformations. It is shown that coupling reactions such as Suzuki and Heck, and reductions such as nitro-to-amine and hydrogenation of olefins can be accomplished in a facile manner by employing Pd@TPAPOP-1 as a heterogeneous recyclable catalyst; the aforementioned transformations have been demonstrated on a broad set of substrates for each type. (C) 2020 Elsevier Inc. All rights reserved.

Formula: C15H12O. About Chalcone, If you have any questions, you can contact Yadav, C; Maka, VK; Payra, S; Moorthy, JN or concate me.

Reference:
Thiazolidine – Wikipedia,
,Thiazolidine – ScienceDirect.com

Name: 1,1,1-Triethoxyethane. Recently I am researching about BEARING PENTAFLUOROSULFANYL GROUPS; GAMMA-LACTONES; FLUORINE; SF5; SUBSTITUENTS; INHIBITORS; CHEMISTRY; ACID; OXYTRIFLUOROMETHYLATION; TRIFLUOROMETHYL, Saw an article supported by the . Published in WILEY-V C H VERLAG GMBH in WEINHEIM ,Authors: Roudias, M; Gilbert, A; Paquin, JF. The CAS is 78-39-7. Through research, I have a further understanding and discovery of 1,1,1-Triethoxyethane

The synthesis of 5-[(pentafluorosulfanyl)methyl]-gamma-butyrolactones bearing different substituents at position 3 or 4 is reported. A silver-promoted intramolecular cyclization of substituted 4-chloro-5-(pentafluorosulfanyl)pentanoic acids allows the preparation of the substituted SF5-containing gamma-butyrolactones in up to 96 % yield.

Name: 1,1,1-Triethoxyethane. About 1,1,1-Triethoxyethane, If you have any questions, you can contact Roudias, M; Gilbert, A; Paquin, JF or concate me.

Reference:
Thiazolidine – Wikipedia,
,Thiazolidine – ScienceDirect.com

Name: 1,1,1-Triethoxyethane. Recently I am researching about BASE EXCISION-REPAIR; COLI FPG PROTEIN; ESCHERICHIA-COLI; ZINC-FINGER; ABASIC SITE; BIOLOGICAL EVALUATION; AROMATIC DISULFIDES; CRYSTAL-STRUCTURE; DAMAGE; 8-OXOGUANINE, Saw an article supported by the Ligue contre le cancer du Grand-Ouest (CSIRGO); Region Centre-Val de LoireRegion Centre-Val de Loire [2013-00082978, 2017-00117252]; radiation protection board of France Electricity (EDF) [RB2015-10]; Canceropole Grand-Ouest (project CONCERTO) [2018-001240994]; University of Orleans; Ligue nationale contre le cancerLigue nationale contre le cancer. Published in MDPI in BASEL ,Authors: Rieux, C; Goffinont, S; Coste, F; Tber, Z; Cros, J; Roy, V; Guerin, M; Gaudon, V; Bourg, S; Biela, A; Aucagne, V; Agrofoglio, L; Garnier, N; Castaing, B. The CAS is 78-39-7. Through research, I have a further understanding and discovery of 1,1,1-Triethoxyethane

DNA glycosylases are emerging as relevant pharmacological targets in inflammation, cancer and neurodegenerative diseases. Consequently, the search for inhibitors of these enzymes has become a very active research field. As a continuation of previous work that showed that 2-thioxanthine (2TX) is an irreversible inhibitor of zinc finger (ZnF)-containing Fpg/Nei DNA glycosylases, we designed and synthesized a mini-library of 2TX-derivatives (TXn) and evaluated their ability to inhibit Fpg/Nei enzymes. Among forty compounds, four TXn were better inhibitors than 2TX for Fpg. Unexpectedly, but very interestingly, two dithiolated derivatives more selectively and efficiently inhibit the zincless finger (ZnLF)-containing enzymes (human and mimivirus Neil1 DNA glycosylases hNeil1 and MvNei1, respectively). By combining chemistry, biochemistry, mass spectrometry, blind and flexible docking and X-ray structure analysis, we localized new TXn binding sites on Fpg/Nei enzymes. This endeavor allowed us to decipher at the atomic level the mode of action for the best TXn inhibitors on the ZnF-containing enzymes. We discovered an original inhibition mechanism for the ZnLF-containing Fpg/Nei DNA glycosylases by disulfide cyclic trimeric forms of dithiopurines. This work paves the way for the design and synthesis of a new structural class of inhibitors for selective pharmacological targeting of hNeil1 in cancer and neurodegenerative diseases.

Name: 1,1,1-Triethoxyethane. About 1,1,1-Triethoxyethane, If you have any questions, you can contact Rieux, C; Goffinont, S; Coste, F; Tber, Z; Cros, J; Roy, V; Guerin, M; Gaudon, V; Bourg, S; Biela, A; Aucagne, V; Agrofoglio, L; Garnier, N; Castaing, B or concate me.

Reference:
Thiazolidine – Wikipedia,
,Thiazolidine – ScienceDirect.com